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Amylin Pharmaceuticals Announces Positive Results From Dose-Ranging Clinical Study Of Pramlintide/Metreleptin Combination Treatment For Obesity
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) announced positive results from a 28-week dose-ranging study of pramlintide/metreleptin, a combination treatment comprising pramlintide, an analog of the natural hormone amylin, and metreleptin, an analog of the natural hormone leptin, in overweight and obese patients. This Phase 2 study successfully characterized patients who responded best to treatment and also provided important information to inform dose selection.
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Obama Nominates Hispanic Roman Catholic Theologian For Vatican Ambassador
President Obama has nominated Miguel Diaz, a Cuban-born Roman Catholic and an associate professor of theology at the College of Saint Benedict at St. John"s University in Minnesota, as the next U.S. ambassador to the Vatican, the White House announced on Wednesday, AP/Boston Globe reports. According to the AP/Globe, although the selection of an ambassador for the Vatican does not usually draw much scrutiny, Diaz"s nomination "comes as tensions run high in the U.S. church over Catholics" voice in the public square and the politics of abortion," especially in the wake of the controversy over Obama"s recent speech at the University of Notre Dame. Another potential issue that might arise during Diaz"s confirmation is his support for former Kansas Gov. Kathleen Sebelius (D) during her nomination to be HHS secretary, the AP/Globe reports. Although conservative Catholics expressed anger that Sebelius, who is Catholic, supports abortion rights, Diaz joined 25 other Catholic leaders and scholars who signed a statement supporting her as "a woman of deep faith," citing her record on health care and reducing abortion rates in Kansas, according to the AP/Globe.In January at Obama"s inauguration, Diaz told the Catholic News Service that Obama was "committed to working" with people who defend "life in the womb" and holds much respect for those whose positions he does not agree with. "Wherever we can, we should advance life at all stages," he said. On Wednesday, he declined to comment on his positions on various issues, which he said would be inappropriate before his confirmation hearing. The AP/Globe reports that the next U.S. ambassador to the Vatican would play a prominent role in scheduling a possible meeting in July between Obama and Pope Benedict XVI during Obama"s visit to Italy (Gorski, AP/Boston Globe, 5/28).
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Use Of Lenalidomide In Patients With Multiple Myeloma Having Already Received At Least Two Previous Therapies Approved By NICE, UK
A review of the NICE decision on the approval of lenalidomide is published in a special report Online First and in the July edition of The Lancet Oncology. About 2,000 multiple myeloma sufferers in the UK could benefit from the drug and improve their life expectancy pending a decision by The UK National Institute for Health and Clinical Excellence (NICE). Patients who have received two or more previous therapies could receive lenalidomide, and the cost of cycles beyond the twenty-sixth cycle of treatment would be met by the drug manufacturer.
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Ad Wars Over Health Care Overhaul Heat Up

"The ad wars over the health care campaign are heating up once [again] this week," The New York Times reports. At a speech on Monday, Michael Steele, chairman of the Republican National Committee, released a party television ad "which its spokeswoman says will first be broadcast in Arkansas, North Dakota and Nevada." The ad "opens with a tiny infant, and spools out with a narrator"s voice saying: "They"ve loaned Barack Obama their future, without even knowing it. Trillions for rushed government bailouts and takeovers, banks, the auto industry." And then it continues, as children appear on the screen: "The biggest spending spree in our nation"s in history. And they"ll have to pay. The next big ticket item? A risky experiment with our health care. Barack Obama"s massive spending experiment hasn"t healed our economy. His new experiment risks their future and our health."" "In another campaign, the American Cancer Society Cancer Action Network bought virtually all of the summer ad space in the Capitol South metro station just south of the Capitol, a stop that"s frequented by members of Congress, their staffs, and Hill visitors. The group said it hoped the installment of banners, holograms and before-and-after patient photos "enflames peoples" passions and encourages political will "to quickly reform health care"" (Southall, 7/20). "Opponents and proponents of the [health care] measures are intensifying their rhetoric and saturating the media to move public support to their sides," McClatchy reports. "Political analysts and advocates predict that the rhetoric from Obama and lawmakers combined with the ad wars from interest groups will be sharper and more superheated than the 1993 public debate over President Bill Clinton and former first lady Hillary Clinton"s failed health care plan." Darrell West, "the vice president and director of governance studies at the Brookings Institution, a public policy research center, said the debate was just getting started, particularly on the advertising side" (Douglas, 7/20). Major business groups are launching their own ad campaigns, The Wall Street Journal reports. "The U.S. Chamber of Commerce, which represents three million employers, plans to introduce a sharply worded multimedia advertising campaign in the next several days pushing back against the key planks of Democrats" health overhaul proposals." And "separately, America"s Health Insurance Plans, the nation"s largest health insurance lobby, on Monday launched a television advertising campaign costing at least $1 million, with ads that say the industry supports the idea of health overhaul -- but only one that is bipartisan. So far, no Republicans have voted for the measures passed through committees in the Democratic-led Senate and House" (Adamy, 7/20). Meanwhile, grass-roots progressives are targeting Senate Finance Committee Chairman Max Baucus, D-Mont., Politico reports. "Democracy for America and the Progressive Change Campaign Committee conducted a four-day, online poll of their members, and with about 64,000 votes cast, Baucus beat seven other Democratic senators as the lawmaker whose arm is most in need of twisting over health care reform. And so on Wednesday, an ad will begin airing in Montana charging Baucus with choosing monied interests over average voters who want the public insurance option." The ads are "the latest escalation in the Democrat versus Democrat ad wars over health care reform. With all but a handful of Republicans opposed to President Barack Obama"s plan, advocacy groups have spent their money almost entirely targeting wayward and undecided Democrats." And "even the president"s political operation, Organizing for America, couldn"t resist a TV campaign aimed at lassoing members of his own party. The group stepped up its effort last week, putting up an ad in more than a dozen states targeting swing Senate and House members, including three Republicans on the House Energy and Commerce Committee." Health Care For America Now also "elevated its efforts last week" with an ad campaign in nine states "focusing primarily on the fiscally conservative Blue Dog Coalition, which has slowed legislation in the House" (Brown, 7/21). Kaiser Health News analyzes the ad campaign of Healthy Economy Now, "an "odd bedfellows" coalition" made up of "the Pharmaceutical Research and Manufacturers of America (PhRMA), AARP, the American Medical Association, the Advanced Medical Technology Association, Business Roundtable, Families USA and the Service Employees International Union. This is the third ad the coalition has released in an ad buy that has totaled more than $12 million. The goal of the ads is to press the fiscally conservative Blue Dog Democrats, who have been snarling about the cost of a health care overhaul and other issues, to support the House bill. The ad urges people to call congressmen who have expressed reservations to ask them to support the legislation" (Villegas, 7/21). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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