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As The Market Potential Grows, Developers Press For Keys To Delivering Systemic Drugs Via Inhalation
At a time when the drug industry is striving for patient-friendly delivery methods for new and existing drugs, the growing availability of innovative inhaler device designs is driving interest in pulmonary drug delivery technology and devices as an alternative to oral and parenteral routes of administration. While well-established for treating upper respiratory diseases such as asthma and COPD, companies competing in the inhaled drug delivery sector - major players such as GlaxoSmithKline, AstraZeneca and Boehringer Ingelheim as well as pure-play start-ups - continue to view delivery of systemic drugs via inhalation as a major opportunity.
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NHS Instructed To Plan For Up To 65,000 Swine Flu Deaths, UK
In a week that has seen the British swine flu death toll reach 29 and it is estimated that 55,000 people have caught the virus, hospitalizing 652 of them, the
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Radiation Dose Drastically Reduced During Whole Chest MDCT
Emergency physicians who evaluate patients with non-specific chest pain using whole chest multi-detector CT (MDCT) combined with retrospective electrocardiogram (ECG) gating can reduce the patient radiation dose by 71% using MDCT combined with prospective ECG triggering instead, according to a study performed at the University of Washington School of Medicine, Seattle, WA. Prospective ECG triggering enables the CT scanner to monitor the ECG signal of several heart beats in real time and turns the radiation beam on only during alternate beats; retrospective ECG gating also monitors the ECG signal of heartbeats but turns the radiation beam on throughout several consecutive beats, thus delivering more radiation.
Endocrinology

Bayer Unveils DIDGET(TM), The First And Only Blood Glucose Meter That Connects With The Nintendo DS(TM) Or DS(TM) Lite

Bayer Diabetes Care in the UK and Ireland today unveils "DIDGET(TM), the first and only blood glucose meter for kids with diabetes that connects directly to Nintendo DS(TM) and Nintendo DS(TM) Lite gaming systems. The DIDGET meter is designed to help kids manage this lifelong condition by rewarding them for building consistent blood glucose testing habits and meeting personalised glucose target ranges. "One of the biggest challenges facing parents of children with diabetes is the constant struggle to instil the habit of regular blood glucose testing that is critical for consistent diabetes management," says John Gregory, Professor in Paediatric Endocrinology, Wales School of Medicine, Cardiff University. "Bayer"s DIDGET meter can help ease the parent/child tension that testing often creates by adding an element of fun and rewards to the routine. Because it is designed with children in mind, Bayer"s DIDGET meter can transform a child"s blood glucose testing experience from something they have to do into something they want to do." Building on 40 years of experience, the company is now transforming how kids engage in their diabetes management by tapping into their existing passion for handheld gaming. Bayer"s DIDGET meter positively reinforces consistent testing habits by awarding points that kids can use to unlock new game levels and customise their gaming experience. "The DIDGET meter is a revolutionary development in healthcare management. Up until now, blood glucose monitors have been created with adults in mind," says Sandra Peterson, Head of Bayer Medical Care. "This product was inspired by a parent of a child with diabetes, to directly address the challenges facing kids with diabetes and their parents. Bayer"s DIDGET meter offers play with purpose to encourage kids to regularly monitor their blood glucose and begin to view regular testing as fun." The DIDGET meter, intended for use by kids aged 5-14, will also connect to Bayer"s DIDGET World (http://www.bayerdidget.co.uk), a new password-protected web community where kids can spend points that they earn from consistent monitoring practices and create their own page. Bayer"s DIDGET World is currently in development and will be available soon. Bayer"s DIDGET meter grows with a child"s ability to manage his/her diabetes, offering two testing levels, Basic and Advanced. Self monitoring blood glucose is an essential tool in the optimal management of childhood and adolescent diabetes. Self monitoring blood glucose should be prescribed at a frequency to optimise each child"s diabetes control because frequency of self monitoring blood glucose correlates with glycaemic control(1). Bayer"s DIDGET meter is based on Bayer"s trusted CONTOUR(R) system and uses the same technology and test strips, providing the same easy accuracy, No Coding(TM) technology, automatic correction for haematocrit and common interfering substances including maltose, 5 second test time, a small (0.6 microL) sample size and automatic detection of control solution. Bayer"s DIDGET meter comes with Knock "Em Downs(TM): World"s Fair which includes a full length adventure game and mini game arcade. Bayer"s DIDGET will be available soon. Visit http://www.bayerdidget.co.uk to find out more and register to be notified when Bayer"s DIDGET meter is available. Nintendo DS and DS Lite gaming systems are sold separately. Bayer Diabetes Care UK is working in partnership with the Juvenile Diabetes Research Foundation (JDRF) in the UK and GBP5 from the sale of every meter will be donated to the JDRF. ÷  Diabetes in the UK An estimated 25,000 children under the age of 18 in the UK have diabetes(2). Type 1 diabetes, also called juvenile diabetes, is usually diagnosed in children and young adults. In persons with type 1 diabetes, the body makes little or no insulin, and therefore people with type 1 diabetes need to take insulin for the rest of their lives (3). Type 2 diabetes is usually diagnosed in adults, although increasingly, children are being diagnosed with this condition. Type 2 is associated with obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, physical inactivity, and race/ethnicity. In people with type 2 diabetes, the body doesn"t make enough insulin, or the body is unable to utilise the insulin effectively. There are many therapies available, including insulin, for people with type 2 diabetes(4). All people with type 1 and type 2 diabetes must carefully balance food, medications, and activity level to keep blood glucose levels as close to normal as possible in order to avoid long term complications of diabetes (5). References 1. Rewers M, Pihoker C, Donaghue K et al. Assessment and monitoring of glycemic control in children and adolescents with diabetes. Pediatric Diabetes 2007: 8: 408-418 2. JDRF UK 3. NHS:÷ Introduction ÷  4. NHS:÷ What is it? 5. NHS: Selfhelp Bayer HealthCare


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