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Identification Of New Breast Cancer-Promoting Gene
A team of researchers, at the Genome Institute of Singapore, has identified a new gene that seems to contribute to aggressive breast cancer behavior. As discussed in an accompanying commentary, by Gordon Mills and colleagues, the data generated in this study provide new insight into cellular processes underlying tumor cell proliferation and metastasis and identify potential new therapeutic targets.
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Study Shows Teen Contraception Use Declining, Level Of Sexual Activity Unchanged
After years of declining teenage pregnancy rates and improved teen contraception use during the 1990s and early 2000s, the trends appeared to have flattened or even reversed among some groups of teens in recent years, according to a study from Columbia University"s Mailman School of Public Health and the Guttmacher Institute, the Christian Science Monitor reports. Researchers found that from 2003 to 2007, teens" contraceptive use declined by 10%, while their level of sexual activity did not change. The decrease in contraceptive use was particularly prevalent among black teens. The figures take into account the rate of contraception use as well as the types of contraceptives used, as methods vary in effectiveness. Teen condom use leveled off and in some cases declined, according to the study. The study also reported that the teen birth rate increased by 5% from 2005 to 2007. According to the study"s authors, the findings suggest a link between declining teen contraception use and the rise in abstinence-only education during former President George W. Bush"s administration. President Obama"s fiscal year 2010 budget proposal calls for redirecting some abstinence-only funds toward increased comprehensive sex education, the Monitor reports. In addition to the effects of abstinence-only sex education, the decline in condom use also could be tied to lessening concern about sexually transmitted infections, including HIV/AIDS. A shift in the teen population to include a higher number of Hispanics -- who have the highest rates of teen pregnancy and birth -- also could contribute to the findings. Laura Lindberg, one of the study"s authors and a senior research associate at Guttmacher, said, "In the end, this story is really about the loss of momentum." She added that although the statistical changes are small, "they raise concern about what the next few years will bring in this country." Sarah Brown, director of the National Campaign To Prevent Teen and Unplanned Pregnancy, noted that the proportion of births to unmarried women, particularly among women ages 20 to 24, also is on the upswing (Feldmann, Christian Science Monitor, 6/18).
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Roux-en-Y Weight Loss Surgery Raises Kidney Stone Risk
The most popular type of gastric bypass surgery appears to nearly double the chance that a patient will develop kidney stones, despite earlier assumptions that it would not, Johns Hopkins doctors report in a new study. The overall risk, however, remains fairly small at about 8 percent.
Endocrinology

Bayer Unveils DIDGET(TM), The First And Only Blood Glucose Meter That Connects With The Nintendo DS(TM) Or DS(TM) Lite

Bayer Diabetes Care in the UK and Ireland today unveils "DIDGET(TM), the first and only blood glucose meter for kids with diabetes that connects directly to Nintendo DS(TM) and Nintendo DS(TM) Lite gaming systems. The DIDGET meter is designed to help kids manage this lifelong condition by rewarding them for building consistent blood glucose testing habits and meeting personalised glucose target ranges. "One of the biggest challenges facing parents of children with diabetes is the constant struggle to instil the habit of regular blood glucose testing that is critical for consistent diabetes management," says John Gregory, Professor in Paediatric Endocrinology, Wales School of Medicine, Cardiff University. "Bayer"s DIDGET meter can help ease the parent/child tension that testing often creates by adding an element of fun and rewards to the routine. Because it is designed with children in mind, Bayer"s DIDGET meter can transform a child"s blood glucose testing experience from something they have to do into something they want to do." Building on 40 years of experience, the company is now transforming how kids engage in their diabetes management by tapping into their existing passion for handheld gaming. Bayer"s DIDGET meter positively reinforces consistent testing habits by awarding points that kids can use to unlock new game levels and customise their gaming experience. "The DIDGET meter is a revolutionary development in healthcare management. Up until now, blood glucose monitors have been created with adults in mind," says Sandra Peterson, Head of Bayer Medical Care. "This product was inspired by a parent of a child with diabetes, to directly address the challenges facing kids with diabetes and their parents. Bayer"s DIDGET meter offers play with purpose to encourage kids to regularly monitor their blood glucose and begin to view regular testing as fun." The DIDGET meter, intended for use by kids aged 5-14, will also connect to Bayer"s DIDGET World (http://www.bayerdidget.co.uk), a new password-protected web community where kids can spend points that they earn from consistent monitoring practices and create their own page. Bayer"s DIDGET World is currently in development and will be available soon. Bayer"s DIDGET meter grows with a child"s ability to manage his/her diabetes, offering two testing levels, Basic and Advanced. Self monitoring blood glucose is an essential tool in the optimal management of childhood and adolescent diabetes. Self monitoring blood glucose should be prescribed at a frequency to optimise each child"s diabetes control because frequency of self monitoring blood glucose correlates with glycaemic control(1). Bayer"s DIDGET meter is based on Bayer"s trusted CONTOUR(R) system and uses the same technology and test strips, providing the same easy accuracy, No Coding(TM) technology, automatic correction for haematocrit and common interfering substances including maltose, 5 second test time, a small (0.6 microL) sample size and automatic detection of control solution. Bayer"s DIDGET meter comes with Knock "Em Downs(TM): World"s Fair which includes a full length adventure game and mini game arcade. Bayer"s DIDGET will be available soon. Visit http://www.bayerdidget.co.uk to find out more and register to be notified when Bayer"s DIDGET meter is available. Nintendo DS and DS Lite gaming systems are sold separately. Bayer Diabetes Care UK is working in partnership with the Juvenile Diabetes Research Foundation (JDRF) in the UK and GBP5 from the sale of every meter will be donated to the JDRF. ÷  Diabetes in the UK An estimated 25,000 children under the age of 18 in the UK have diabetes(2). Type 1 diabetes, also called juvenile diabetes, is usually diagnosed in children and young adults. In persons with type 1 diabetes, the body makes little or no insulin, and therefore people with type 1 diabetes need to take insulin for the rest of their lives (3). Type 2 diabetes is usually diagnosed in adults, although increasingly, children are being diagnosed with this condition. Type 2 is associated with obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, physical inactivity, and race/ethnicity. In people with type 2 diabetes, the body doesn"t make enough insulin, or the body is unable to utilise the insulin effectively. There are many therapies available, including insulin, for people with type 2 diabetes(4). All people with type 1 and type 2 diabetes must carefully balance food, medications, and activity level to keep blood glucose levels as close to normal as possible in order to avoid long term complications of diabetes (5). References 1. Rewers M, Pihoker C, Donaghue K et al. Assessment and monitoring of glycemic control in children and adolescents with diabetes. Pediatric Diabetes 2007: 8: 408-418 2. JDRF UK 3. NHS:÷ Introduction ÷  4. NHS:÷ What is it? 5. NHS: Selfhelp Bayer HealthCare


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