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Abnormal Brain Circuits May Prevent Movement Disorder
Most people who carry a genetic mutation for a movement disorder called dystonia will never develop symptoms, a phenomenon that has puzzled scientists since the first genetic mutation was identified in the 1990"s. Now, scientists at The Feinstein Institute for Medical Research have figured out why these mutation carriers are protected from symptoms of the disorder they have an additional lesion that evens the score.

Rosiglitazone For Type 2 Diabetes Does Not Increase Risk Of Cardiovascular Disease Or Death But Increases Heart Failure And Fractures In Women
Using rosiglitazone (Avandia) in combination with standard diabetes treatments (metformin or a sulfonylurea) to lower blood glucose in type 2 diabetics does not increase the risk of cardiovascular disease or death. However, the study confirms that using rosiglitazone more than doubles the risks of heart failure, and also increases the risk of fractures, mainly in women. The findings of the RECORD study are published in an Article Online First and in an upcoming edition of The Lancet. They are being simultaneously presented at the American Diabetes Association (ADA) meeting in New Orleans, USA.
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Government Of Canada Approves A New Of Medical Isotopes
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Common Migraine Pain Condition Also Prevalent In Cluster Headache

A pain condition common in people with migraines also has a high prevalence in patients with cluster headache, according to a study conducted by researchers at the Jefferson Headache Center at Jefferson Hospital for Neuroscience. Approximately half of a group of patients with cluster headaches experienced cutaneous allodynia, a condition that causes patients to have pain as a response to normally inconspicuous sensations, according to Michael Marmura, M.D., assistant professor of Neurology at Jefferson Medical College of Thomas Jefferson University. The study, which was published in the Journal of Headache and Pain, included 41 patients with either chronic or episodic cluster headaches. The researchers tested for allodynia by brushing a gauze pad over the forehead, neck and forearms. Patients then reported if the gauze was painful or unpleasant, or not. Twenty of the patients experienced allodynia, with the most common site of pain being the forehead. There were no significant differences between patients who experienced allodynia and patients who did not. The majority of patients were using preventive medications, which is a limitation of the study. According to Dr. Marmura, allodynia has typically been described in migraines, but this is the largest study to date showing that allodynia occurs in cluster headache. "It was surprising to find that allodynia was so common in patients with cluster headaches," Dr. Marmura said. "This could have important treatment implications, and suggests that there may be overlap in mechanisms for pain between migraines and cluster headaches." Thomas Jefferson University


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