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South American Health Ministers Gather In Argentina To Discuss H1N1 Preparedness
The health ministers of six South American countries gathered in Buenos Aires, Argentina, on Wednesday to "coordinate defenses against" the H1N1 (swine flu) virus which has killed nearly 200 people in the region," the AFP/Google.com reports. Ministers from Argentina, Bolivia, Brazil, Chile, Paraguay and Uruguay used the meeting to voice concern over the rapid spread of the H1N1 virus in their countries, which are now in the southern hemisphere"s winter months, and discuss ways to share supplies to help prevent the spread of the virus. The article includes the individual strategies being taken by some South American countries (7/15).

Fertility Donor Debate, UK
Dr Gedis Grudzinskas the UK-based fertility expert issued the following statement in response to the statement by the Human Fertilisation and Embryology Authority:
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HIV/AIDS Vaccine Coalition Urges Continued Funding For Research Amid Economic Crisis
A recently released AIDS Vaccine Advocacy Coalition report says that although there has been a renewed focus on discovery, innovation and basic science in vaccine research, action is needed to ensure that research funding continues during the economic downturn, VOA News reports. AVAC executive director Mitchell Warren said the report is "about putting all the pieces together ... not just the search for an AIDS vaccine, but in fact the entire HIV prevention response." He added, "[T]he good news is we have some new pieces of the puzzle, and we"re expecting additional new pieces of understanding through research this year." Warren said that AVAC believes HIV/AIDS vaccine research is in "one of the most exciting times," with "new energy, new commitment to unlocking some of the basic scientific roadblocks that have impeded our ability to find a vaccine." For example, a study released earlier this week examined efforts to produce a vaccine through genetic transfer. Regarding the study, Warren said, "It doesn"t mean we have an AIDS vaccine, but it means we have an entirely new approach to trying to deliver protection." Warren said that the field of HIV/AIDS vaccine research has shown a renewed commitment since Merck canceled its vaccine trial in 2007. According to Warren, the new AVAC report examines knowledge gained from the Merck study, which has provided "an unimaginable amount of information." Meanwhile, the effect of the economic crisis on research funding is concerning, Warren said, adding, "I believe that every dollar spent is going to be held up to a greater scrutiny as budgets tighten and as funders have to re-examine their priorities." According to Warren, without renewed funding commitments, "we will not only incur a much greater public health catastrophe, but I would argue that the economic catastrophes to come, if we don"t respond aggressively to HIV, will actually have repercussions that will ... make the economic crisis pale in comparison" (DeCapua, VOA News, 5/18).
Cardiovascular

Foresight Biotherapeutics Announces Initiation Of Viral Conjunctivitis Clinical Trial

Foresight Biotherapeutics announced that the first patient has been dosed in a viral conjunctivitis clinical trial. Foresight"s proprietary lead compound, FST-100, will be tested in a placebo-controlled, masked, and randomized multicenter clinical study throughout the United States. The primary endpoint of the study is the resolution of clinical signs and symptoms of acute conjunctivitis. Secondary endpoints include a reduction in quantitative PCR (qPCR) viral titers, eradication of infectious virus determined by cell culture immunofluorescence assay (CC-IFA), and safety. The company anticipates enrolling up to 100 patients. This controlled clinical trial follows a successful pilot trial in which the safety and efficacy of FST-100 were demonstrated. In addition, the company recently completed and announced a successful preclinical study in a rabbit model of adenoviral conjunctivitis. Viral conjunctivitis or "pink eye" is the most common eye infection in the developed world. The highly contagious infection is a frequent cause of epidemics in the workplace, schools, medical centers and long term care facilities. Treatment is mostly supportive as there is currently no drug approved by the FDA for viral conjunctivitis. FST-100 is a novel formulation of dexamethasone that includes povidone-iodine. This novel formulation may be able to relieve the discomfort and shorten the course of the illness. Foresight Biotherapeutics looks forward to working with the investigators in conducting this clinical trial and advancing the development of the program. Foresight Biotherapeutics, Inc.


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