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Lupus Drug Benlysta Effective In Phase 3 Trials
In what has been described as the first lupus drug in decades to show effectiveness in phase 3 clinical trials, the announcement that Benlysta

Medical Device Development: Stanford Researchers Publish Comprehensive Model
In an effort to increase understanding of the medical device development process and help companies execute the bench-to-bedside process of product development more effectively, researchers at Stanford University have published the first comprehensive model representing the medical device development process.
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In Metastatic Kidney Cancer, 2-Drug Combination Appears Safe And Active
Fox Chase Cancer Center investigators report that a two-drug blockade of mTOR signaling appears safe in metastatic kidney cancer in a phase I trial. Early data suggests that a combination of temsirolimus and bryostatin may be active in patients with rare forms of renal cell cancer, which are less likely to respond to other targeted therapies.
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Healing Wounds With Lasers

Researchers from around the world will present the latest breakthroughs in electro-optics, lasers and the application of light waves at the 2009 Conference on Lasers and Electro-Optics/International Quantum Electronics Conference (CLEO/IQEC) May 31 to June 5 at the Baltimore Convention Center in Baltimore. HEALING WITH LIGHT Star Trek scanners that fix injuries with beams of light may not be science fiction after all. A new optical technology that lines up living cells and controls their movements has opened the door to better artificial tissues and wounds that heal faster with less scarring. For years, scientists have used the energy in laser light to drill microscopic holes or as tweezers or traps to direct and maneuver small pieces of matter. Guiding entire cells, though, has proven difficult because the lasers used for manipulation tend to damage the structural units of living organisms. Now Aristide Dogariu and colleagues at the University of Central Florida in Orlando have developed an optical procedure that does not harm cells, but affects their skeletons - an ensemble of slender rods made out of an abundant protein called actin. The actin rods are constantly growing and shrinking inside of cells. The direction in which they grow changes the cell"s membrane shape and dictates where the cell moves. Dogariu and colleagues use the polarization of optical waves to create a field around the cells in which the growing actin rods line up like a compass in the Earth"s magnetic field. These optical fields can be used to guide large groups of cells to line up and move in the same direction. The technique could be useful for cancer assays, which test the motility of cells, or as a non-invasive, non-toxic boost for regenerative medicine. Though cells have complicated and intriguing mechanisms to sense and communicate where an injury occurs, the possibility of using photonic scaffolds to stimulate and guide cells" motility to accelerate tissue repair, is now quite promising. Presentation CMMM2; Monday, June 1, 4 - 4:15 p.m. Colleen Morrison Optical Society of America


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