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Epeius Biotechnologies' Rexin-G Receives FDA Fast Track Designation For The Treatment Of Pancreatic Cancer
Epeius Biotechnologies announced that its lead product, Rexin-G, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for use as a second-line treatment for advanced or metastatic pancreatic cancer. The FDA Fast Track program, like Priority Review and Accelerated Approval, was implemented to facilitate the development and expedite the review of potentially important new drugs. The Fast Track Product designation, in particular, is granted following a critical evaluation of the "seriousness" or life-threatening nature of the unmet medical need, namely pancreatic cancer, and the potential of Rexin-G and its progressive clinical development to address this unmet need.

ThromboGenics And BioInvent Start Recruitment Of Second 100 Patient Cohort In Phase II DVT Prophylaxis Study With TB-402
ThromboGenics NV (Euronext Brussels: THR) and co-development partner BioInvent International (OMXS: BINV) announce that they have started recruitment of a second cohort of patients for their Phase II trial of TB-402. This follows completion of recruitment of the first cohort of 100 patients ahead of schedule. TB-402 is a novel, long acting anticoagulant that is being developed for the prevention of deep vein thrombosis (DVT) following orthopaedic surgery. The decision to move ahead with the second cohort of this trial follows unanimous advice from the external efficacy and safety monitoring board to proceed using a higher dose of TB-402.
News of the day
Novel Epigenetic Markers Of Melanoma May Herald New Treatments For Patients
Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment. In a study published online in Genome Research, scientists have mapped chemical modifications of DNA in the melanoma genome, finding new markers that will help develop more effective treatment strategies to fight this disease.
Mental Health

Maine CDC Issues Carbon Monoxide Poisoning Advisory For Those Opening Their Summer Camps, USA

The Maine Center for Disease Control and Prevention of the Maine Department of Health and Human Services, is issuing an advisory about the danger of carbon monoxide poisoning when people open camps for the summer. Health officials urge camp owners to make sure their propane-fueled stoves and/or refrigerators are operating properly and safely when turned on for the season. They should also make sure they have a working carbon monoxide detector close to where people sleep. "Last spring we saw several poisonings in which family members were exposed to high levels of carbon monoxide because of poorly maintained gas-fueled appliances. Some of these poisonings were life-threatening," said State Toxicologist Dr. Andrew Smith. Though early in the season, state health officials have already investigated two camp-related incidents involving carbon monoxide poisoning. The Maine CDC recently made carbon monoxide poisoning a reportable disease and now investigates the causes of all reported poisonings. "Tgus change in reporting will help us identify the causes of carbon monoxide poisonings so we can better inform the public about ways to prevent these hazards," said Smith said. Each year, there are more than 100 emergency department admissions in Maine due to carbon monoxide poisoning, with between one and five deaths. Carbon Monoxide (CO) is an odorless colorless gas emitted when burning most fuels. Improper venting, maintenance, operation or placement of combustion devices can result in poisoning when CO gas builds up in enclosed spaces. CO interferes with the delivery of oxygen to body tissues. Warning signs of CO poisoning are flu-like symptoms, including headache, nausea, vomiting, dizziness, drowsiness, and confusion, but no fever. CO poisoning can cause coma and death. "The best way to prevent CO poisoning is to make sure combustion devices are well-maintained, regularly serviced, and operated properly," said State Health Officer Dr. Dora Anne Mills. "A carbon monoxide detector with back-up battery power should be placed near every sleeping area." The Maine State Legislature passed a new law this session that requires carbon monoxide detectors to be installed in all apartments and new single-family dwellings. Detectors are also required in existing single-family dwellings whenever there is a transfer of ownership or the addition of at least one new bedroom. For information on the new State law requiring carbon monoxide detectors, click here. Maine Center for Disease Control and Prevention


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