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Key To Potential New Treatment For Allergy-Induced Asthma Identified By Yale Team
In research that could lead to new asthma drugs, scientists at Yale School of Medicine, Hydra Biosciences of Cambridge, Massachusetts, and the University of California, San Francisco have discovered that a protein may be a trigger of allergy-induced asthma in mice. They also demonstrated how a drug known to reduce inflammatory and neuropathic pain may also inhibit asthma symptoms in mice. Their paper is published in the May 18-22 online Early Edition of the Proceedings of the National Academy of Sciences.

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P[acman]-Generated Fruit Fly Gene 'Library': A New Research Tool
Using a specially adapted tool called P[acman], a collaboration of researchers led by Baylor College of Medicine has established a library of clones that cover most of the genome of Drosophila melanogaster (fruit fly) and should speed the pace of genetic research.
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Foresight Biotherapeutics Announces Initiation Of Viral Conjunctivitis Clinical Trial
Foresight Biotherapeutics announced that the first patient has been dosed in a viral conjunctivitis clinical trial. Foresight"s proprietary lead compound, FST-100, will be tested in a placebo-controlled, masked, and randomized multicenter clinical study throughout the United States. The primary endpoint of the study is the resolution of clinical signs and symptoms of acute conjunctivitis. Secondary endpoints include a reduction in quantitative PCR (qPCR) viral titers, eradication of infectious virus determined by cell culture immunofluorescence assay (CC-IFA), and safety. The company anticipates enrolling up to 100 patients.
Endocrinology

Tufts Health Plan Foundation Grant Awarded To Hebrew SeniorLife

Hebrew SeniorLife has received a $105,000 grant from the Tufts Health Plan Foundation for the expansion and implementation of three evidence-based healthy aging programs designed to disseminate preventive health-related information to seniors in the community. "This expansion will educate more than 500 more seniors on nutrition, exercise and falls prevention, helping to maintain their overall health and independence," says Robert Schreiber, M.D., HSL"s physician-in-chief. "The prevention education will additionally reflect a cost-effective method of avoiding hospitalizations and treatments for diseases and disabilities." Since 2004, HSL has trained more than 200 leaders in the implementation of three evidenced-based healthy aging programs - on proper nutrition, exercise and falls - at 30 community organizations. The Tufts grant will enable HSL to leverage its training experience and administrative support to educate 80 more leaders using a "train-the-trainer" model and coordinate program implementation at 50 senior centers and housing sites in Worcester, Burlington, Cambridge, Lawrence and Brockton, among other communities. In addition, HSL will utilize its partnership with Harvard"s Multi-Cultural Coalition on Aging, a network of community leaders from culturally diverse neighborhoods, to recruit and retain program participants from Thai, Vietnamese, Hispanic and other minority senior populations. "This grant establishes us as a training center of excellence and also provides funding for a culturally competent translation of one or more of these programs," says Jennifer Raymond, director of evidence-based programs at HSL. Healthy Eating for Successful Living in Older AdultsTM is a program for seniors who want to learn more about nutrition and how lifestyle changes can promote better health. A Matter of Balance is specifically designed to reduce the fear of falling, stop the cycle of falling, and increase activity levels among community-dwelling older adults. Fit For Your LifeTM is a research-based program developed by HSL"s Institute for Aging Research as a safe, effective exercise option for frail elders. Scott Edwards Hebrew SeniorLife Institute for Aging Research


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