Diagnostics
A virus (from the Latin virus meaning toxin or poison) is a microscopic organism consisting of genetic material (RNA or DNA) surrounded by a protein, lipid (fat), or glycoprotein coat. Viruses are unique organisms because they cannot reproduce without a host cell. After contacting a host cell, a virus will insert genetic material into the host and take over the host"s functions. The cell, now infected, continues to reproduce, but it reproduces more viral protein and genetic material instead of its usual products. It is this process that earns viruses the classification of "parasite".
Stem Cell Therapeutics Corp. (TSX VENTURE:SSS)("SCT" or "the Company") has received a No Objection Letter ("NOL") from Health Canada for the modified REGENESIS protocol using NTx®-265 for a Phase IIb clinical trial treating acute ischemic stroke.
"As the U.S. Supreme Court prepares to consider a restaurant group"s challenge to San Francisco"s health coverage ordinance, one voice is noticeably silent: the Obama administration"s," The San Francisco Chronicle reports. "In contrast to President George W. Bush"s Labor Department, which unsuccessfully urged a federal appeals court to overturn the groundbreaking law, the new administration submitted no arguments before the July 10 deadline for briefs supporting or opposing Supreme Court review. President Obama, meanwhile, has praised the San Francisco program, the first of its kind in the nation, while pressing Congress to enact comprehensive health coverage."
Eurand N.V. (NASDAQ: EURX), a specialty pharmaceutical company that develops enhanced pharmaceutical and biopharmaceutical products based on its proprietary pharmaceutical technologies, announced that the Dutch Medicines Evaluation Board (MEB) informed the Company that the Decentralized Procedure (DCP) for registration of Paracetamol 250 and 500 mg Orodispersible Tablets (ODT) in several EU countries has been successfully completed.
Secondhand smoke (SHS) is not only a nuisance, but a potential health concern for many college students, and administrators should be taking steps to reduce students" exposure, according to a new study by researchers at Wake Forest University School of Medicine.
The results of a recent study published in PNAS question the long-term effects of transplanted cells in the brains of patients suffering from Huntington"s disease. This study, conducted jointly by Dr. Francesca Cicchetti of Universitç© Laval in Quebec, Canada, Dr. Thomas B. Freeman of the University of South Florida, USA, and colleagues provides the first demonstration that transplanted cells fail to offer a long-term replacement for degenerating neurons in patients with Huntington"s disease.
A team of researchers, at the Genome Institute of Singapore, has identified a new gene that seems to contribute to aggressive breast cancer behavior. As discussed in an accompanying commentary, by Gordon Mills and colleagues, the data generated in this study provide new insight into cellular processes underlying tumor cell proliferation and metastasis and identify potential new therapeutic targets.
Scientists have identified a master regulator gene for early embryonic development of the pancreas and other organs, putting researchers closer to coaxing stem cells into pancreatic cells as a possible cure for type1 diabetes.
Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL), a specialty biopharmaceutical company, announced that new data from the two-part HYHYHI Study (Hypogonadal Hypotestosteronism in HIV-Seropositive Men) were presented as a poster today at the 5th International AIDS Society (IAS) Conference in Cape Town, South Africa. This retrospective chart review, supported by the Company, evaluated the challenges associated with diagnosing low testosterone in men with HIV/AIDS. The study also compared the difference in testosterone levels achieved after 12 months of treatment with either Testim® 1% (testosterone gel) or AndroGel®, two commonly used FDA-approved testosterone replacement products.
Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring the virus - centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the study subjects who received the vaccine by increasing Ad5-specific CD4+ T-cells that were susceptible to HIV-1 infection.
Prenatal exposure to environmental pollutants known as polycyclic aromatic hydrocarbons (PAHs) can adversely affect a child"s intelligence quotient or IQ, according to new research by the the Columbia Center for Children"s Environmental Health (CCCEH) at the Mailman School of Public Health. PAHs are chemicals released into the air from the burning of coal, diesel, oil and gas, or other organic substances such as tobacco. In urban areas motor vehicles are a major of PAHs. The study findings are published in the August 2009 issue of Pediatrics.
Compared with patients with moderately controlled glucose levels, diabetic patients who have heart failure and either too high or too low glucose levels may be at increased risk of death, said researchers at Baylor College of Medicine in a report published in the current issue of Journal of the American College of Cardiology.
Stagnation in HIV/AIDS funding and the high cost of new medicines are putting the lives of thousands of poor patients at risk, the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) warned today at the 2009 International AIDS Society conference in South Africa . Patients needing new drug regimens will return to AIDS "death row." While the lack of access to antiretroviral treatment for seven million people remains unaddressed, inadequate financing now further threatens treatment scale-up.
General Practitioners and specialists will be able to prescribe VFEND® (voriconazole) oral suspension for immuno-suppressed adolescents and children following its listing on the Pharmaceutical Benefits Scheme (PBS) from 1 August 2009.
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that treatment with its cancer drug candidate INNO-206 resulted in a statistically significant reduction in the average primary tumor size in an animal model of pancreatic cancer, outperforming the broadly used chemotherapeutic drug doxorubicin, as well as the current standard of care in pancreatic cancer treatment, gemcitabine.
Across the state of Maryland, there are now doctors and nurses, freshly trained in pediatric dental health care, who can help stem an alarming number of 3-year-old children who arrive for their first dentist visit with teeth "just melting away."
An international team of researchers led by scientists at the Mayo Clinic campus in Florida have found what they believe is the first mutated gene linked to restless legs syndrome, a common neurologic disorder.
In the past decade the popularity of rock climbing has dramatically increased. It has been estimated that rock climbing is now enjoyed by more than 9 million people in the U.S. each year. A new study by researchers at the Center for Injury Research and Policy of the Research Institute at the Nationwide Children"s Hospital found that as the popularity of the sport has escalated, so have the number of injuries. Study findings revealed a 63 percent increase in the number of patients that were treated in U.S. emergency departments for rock climbing-related injuries between 1990 and 2007.
Reproductive health experts were "taken aback" by a recent study that found that the withdrawal method is nearly as effective as male condoms in preventing pregnancy, the New York Times reports. The paper -- published in the June issue of the journal Contraception -- found that 4% of couples will become pregnant over a one-year period if they consistently use the withdrawal method, compared with about 2% of couples that consistently use condoms. According to the study"s authors, a more significant finding was that the rate of "typical use" for withdrawal leads to pregnancy 18% of the time, compared with 17% of the time for typical use of condoms. They wrote in the study that "it is unfortunate that some couples do not realize they are substantially reducing their risk of pregnancy when using withdrawal, as these misperceptions may cause unnecessary levels of anxiety. More speculatively, if more people realized that correct and consistent use of withdrawal substantially reduced the risk of pregnancy, they might use it more effectively." Although the authors said the goal of the paper was to encourage discussion, some experts are concerned that spreading a message that withdrawal is effective could lead young people to have unprotected sex, potentially exposing themselves to sexually transmitted infections that can be prevented through condom use, the Times reports. Melissa Gilliam, chief of family planning and contraceptive research at the University of Chicago"s Department of Obstetrics and Gynecology and a board member of the Guttmacher Institute, said the study"s data "don"t necessarily translate to youth today." She added, "In terms of a reliable method used over and over again, the risk of failure is quite high."Rachel Jones, the lead author of the study and a senior research associate at Guttmacher, said that dismissing the withdrawal method as a "legitimate" form of contraception is "counterproductive for the prevention of pregnancy and also discourages academic inquiry into this frequently used and reasonably effective method." She also said that health educators and providers "should discuss withdrawal as a legitimate, if slightly less effective, contraceptive method in the same way they do condoms and diaphragms." She noted that "most women have used withdrawal at some point in their lives."The study"s authors decided to examine the issue after noticing that many researchers and providers "just kind of dismiss withdrawal and don"t seem to realize that it can prevent pregnancy," according to Jones. She added, "Most people seem to be under the impression that you might as well do nothing." Martha Kempner, vice president for information and communications at the Sexuality Information and Education Council of the United States, said the results of the study have "made some classroom teachers nervous to give out the truth in this instance, but we do have to tell the truth." She added, "People, kids in particular, they"re using it. It is better than nothing, and it is always available" (Belluck, New York Times, 7/21).
The following summarizes selected women"s health-related blog entries. ~ ""Operation Rescue" Founder Warns of "Violent Convulsions" if Health Bill Doesn"t Ban Abortions," Ian Millhiser, Think Progress: Operation Rescue founder Randall Terry is "probably the first public figure to raise terrorism as a potential response to a health bill which allows Americans to keep the same access to reproductive care that they currently enjoy," Millhiser writes in a blog post responding to Terry"s warning "that his supporters may engage in violent acts of terrorism unless Congress prohibits abortion services from being covered in the new health reform legislation." According to Millhiser, Terry recently said that there are some people ""who will be tempted to acts of violence"" and that ""history will hold those in power responsible for the violent convulsions that follow"" the legislation. Millhiser writes that many conservative policymakers are "pushing a poison pill amendment" to Congress" reform bill that would prohibit the coverage of abortion services in plans offered within a national health insurance exchange. He notes that 71% of U.S. residents oppose an amendment that would "cut off women"s access to reproductive care" (Millhiser, Think Progress, 7/20).~ "Gestation Is a Life-Changing Experience for Women," Jessica Grose, XX Factor: Grose"s post responds to Francis Kissling"s recent Salon opinion piece discussing the ""new pro-lifers."" According to Grose, this movement "seeks to make bearing and raising children easier, and reducing abortion that way." She continues, "It almost sounds reasonable to pro-choice Kissling, except for one thing: making bearing children "easier" doesn"t acknowledge how gestation can change a woman"s life." According to Kissling, the ""new pro-lifers barely acknowledge the difficulties of childbirth,"" and the movement ""denies the reality that even in modern Western culture, in the high-tech U.S., every woman who agrees to be pregnant still risks dying if the pregnancy goes awry."" Kissling also wrote that the ""new antiabortionists want to use their rosy view of pregnancy as the frame for public policy, and that is where they become indistinguishable from the old antiabortion movement. For both groups, women are passive participants in gestation."" Grose writes that "many of the new pro-lifers don"t support efforts to bring contraception to women who don"t have access to it," an issue that is "likely to come back in a big way in the next few months as the administration"s new health plan is debated" (Grose, XX Factor, 7/20).~ "Thanks, Abstinence-Only Education!" Feministing: "Thanks to a decade of misinformation and masquerading as sex education, teens are having the same amount of sex, using contraception less and getting pregnant more," a Feministing blog entry states. A report from the Centers for Disease Control and Prevention found that trends in reproductive and sexual health of U.S. teens and young adults ""have flattened, or in some instances may be worsening."" According to the blog entry, "We"re reaping what we"ve sowed." Although President Obama"s 2010 budget proposal includes cuts in abstinence-only education funding, "de-funding these programs is not enough," the blog says. It adds, "We have to undo the damage that"s been done to young people and support real solutions." The blog concludes, "The purity-pushers are not going anywhere, but this is about more than politics, ... it"s about our health and futures" (Feministing, 7/20).~ "Human Rights Resolution Spotlights Disparities in Maternal Health Care in the U.S.," Ximena Andion Ibanez et al., RH Reality Check: A "vast majority" of pregnancy- and childbirth-related deaths are "preventable and can therefore be understood to reflect widespread indifference to the rights of the world"s poorest women," Ibanez writes in a blog post co-authored by Center for Reproductive Rights Deputy Director Laura Katzive and Michelle Movahead, an attorney at the ce
"President Obama is becoming more personally invested in rallying the public and Congress behind a healthcare overhaul, even as some Republicans raise the stakes in the debate by claiming that defeating his plan would undermine his presidency," the Los Angeles Times reports. Obama will defend his push for health reform in a series of public events this week, as he and senior aides press Democratic lawmakers to support the versions of pending legislation still circulating in congressional committees (Parsons and Levey, 7/21).
Democratic leaders may scale back a plan to tax the highest American earners, The New York Times reports.
"The ad wars over the health care campaign are heating up once [again] this week," The New York Times reports. At a speech on Monday, Michael Steele, chairman of the Republican National Committee, released a party television ad "which its spokeswoman says will first be broadcast in Arkansas, North Dakota and Nevada." The ad "opens with a tiny infant, and spools out with a narrator"s voice saying: "They"ve loaned Barack Obama their future, without even knowing it. Trillions for rushed government bailouts and takeovers, banks, the auto industry." And then it continues, as children appear on the screen: "The biggest spending spree in our nation"s in history. And they"ll have to pay. The next big ticket item? A risky experiment with our health care. Barack Obama"s massive spending experiment hasn"t healed our economy. His new experiment risks their future and our health.""
"Emboldened by divided Democrats and polls that show rising public anxiety about President Obama"s handling of health care and the economy, Republicans on Monday launched an aggressive effort to link the two, comparing the health-care bills moving through Congress to what they labeled as a failed economic stimulus bill," The Washington Post reports. "And the news Monday that the Obama administration would delay release of a congressionally mandated report on the nation"s economic conditions only stoked the rhetoric, spawning GOP speculation that the White House is trying to avoid bad news amid the health-care debate. "The last time the president made grand promises and demanded passage of a bill before it could be reviewed, we ended up with the colossal stimulus failure and unemployment near 10 percent," Sen. Jim DeMint (R-S.C.) said. "Now the president wants Americans to trust him again, but he can"t back up the utopian promises he"s making.""
Dietitians of Canada (DC) released a report today describing the integral role played by registered dietitians, as members of multi-disciplinary teams that contribute to promoting and supporting health among Canadians. The Role of Registered Dietitians in Primary Health Care: Moving Forward - A National Perspective presents evidence for the cost-effectiveness of nutrition services in the prevention and treatment of chronic conditions such as diabetes, hypertension, cancer and heart disease.
John Kofi Agyekum Kufuor, a former president of Ghana, has been named a global ambassador against hunger for the U.N."s World Food Programme (WFP), Xinhua reports. According to the news service, Kufuor will "help to underline the importance of fighting hunger on several fronts - by investing in long-term agricultural development, but also by funding WFP"s work in tackling urgent hunger needs and helping the hungry poor to access affordable and nutritious food" (Ooko, 7/20).
Discoveries by Scripps Research Institute scientists have led to a promising new drug candidate - the first in its class - for patients with a genetic protein-misfolding disease. In results announced by the biopharmaceutical firm FoldRx Pharmaceuticals, Inc., the new drug tafamidis significantly halts disease progression for patients with a disease called Transthyretin (TTR) amyloid polyneuropathy (ATTR-PN).
Commenting on the final biennial report from the Mental Health Act Commission released by the Care Quality Commission, Mental Health Network director Steve Shrubb said:
In the new issue of the Developmental Cell journal, a team of scientists at Singapore"s Agency for Science, Technology and Research (A*STAR) and the University of North Carolina School of Medicine at Chapel Hill, report research findings about the molecular mechanisms behind the aging process, which has up till now been poorly understood, that offer the possibility that a novel, pharmacological approach could be developed to combat age-related disorders.
Sol-Gel Technologies Ltd, a specialty pharmaceuticals company, announced today results from a comparative clinical study. The results demonstrate that the company"s two strength Anti-Acne kits achieved pronounced efficacy and markedly improved tolerability. The study will be presented at the 10th International Congress of Dermatology in Prague, May 20-23, 2009.
Taking eye drops multiple times a day can be difficult for patients to do, and because of blinking and tearing, as little as 1 to 7 percent of the dose is actually absorbed by the eye. Now, researchers led by Daniel Kohane, MD, PhD, director of the Laboratory for Biomaterials and Drug Delivery at Children"s Hospital Boston, have developed special contact lenses that can gradually dispense a constant amount of medication to the eye, at adjustable rates. They describe their prototype lens in the July issue of Investigative Ophthalmology and Visual Science.
The Netherlands Institute for Health Services Research (NIVEL) and SDI, a U.S. private-sector healthcare information company, announced the formation of the European Paediatric Influenza Analysis (EPIA) group, created to generate data needed to inform the decision process about paediatric influenza vaccination policy in individual European countries. Researchers from Denmark, England, Finland, Italy, the Netherlands, Scotland, Spain and Wales are participating; it is hoped that other countries will also join. EPIA was formed to address knowledge gaps highlighted in a recent European Centre for Disease Prevention and Control (ECDC) report that concluded that a key barrier to decision-making about paediatric flu vaccines is the lack of high-quality, European-specific data on disease burden, especially for young children. It is estimated by ECDC that at least 40,000 people die each year from influenza in the European Union (EU). EPIA will present the initial results from their research project at the 27th annual meeting of the European Society for Paediatric Infectious Diseases (ESPID) in June.
African American men could be putting their health at risk by avoiding disease screening, in the belief that the results might threaten their masculinity. Because they prove their masculinity through their sexuality and sexual performance, seeking medical advice including HIV/AIDS testing goes against their notion of masculinity. Waverly Duck, a Post Doctoral Associate from the Department of Sociology at Yale University in the US, argues that current leading theories of gender and masculinity and health behavior models are not relevant enough to African American men and their distinctive notion of masculinity. His results1 are published online in Springer"s Journal of African American Studies.
Increasing numbers of children around the world are suffering from respiratory problems - coughing, wheezing and asthma attacks. Although the key external causes of these diseases were identified a long time ago (traffic and industrial air pollution), it had not previously been possible to distinguish clearly between these two factors so as to have a targeted impact on them. Researchers at the Helmholtz Centre for Environmental Research (UFZ) and the University of Leipzig carried out research in this area together with colleagues from the University of La Plata and can now confirm that air pollution caused by industry has even more grave effects than vehicle exhaust fumes.
As the ESC Congress 2009 draws ever closer, the evidence in favour of a healthy lifestyle for the prevention of cardiovascular disease grows ever stronger. Prevention is the highlight theme of this year"s event, which will take place in Barcelona from 29 August to 2 September. Lifestyle factors are heavily on the agenda.
Women who have premature menopause because of medical interventions are at an increased risk of developing lung cancer, according to a new study published in the International Journal of Cancer. The startling link was made by epidemiologists from the Universitç© de Montrç©al, the Research Centre of the Centre Hospitalier de l"Universitç© de Montrç©al and the INRS-Institut Armand-Frappier.
The New York State Senate has passed the
A portable "lab on a chip" that can identify target molecules in blood samples has been created by European researchers. It is being used to measure fertility hormones and detect the genes associated with certain types of cancer.
Several cerebrospinal fluid (CSF) biomarkers showed good accuracy in identifying patients with mild cognitive impairment who progressed to Alzheimer disease, according to a study in the July 22/29 issue of JAMA.
FoldRx Pharmaceuticals, Inc. (FoldRx) announced positive results from its pivotal Phase II/III clinical study of the company"s lead compound, tafamidis (Fx-1006A), in patients suffering from TTR amyloid polyneuropathy (ATTR-PN), a fatal orphan disease also known as Familial Amyloid Polyneuropathy (FAP). Liver transplantation is the only currently available treatment option for this progressive neurodegenerative disease. Preliminary results from the first randomized controlled trial ever completed in this disease demonstrate that tafamidis treatment significantly halts disease progression in ATTR-PN, reduces the burden of disease after 18 months compared to placebo, and appears to be safe and well-tolerated.
Researchers from Cincinnati Children"s Hospital Medical Center have discovered that a specific gene - Sox17 - plays an important role in directing cells to become part of the pancreas or part of the bile duct (used in the digestion of food).
The Health and Safety Executive (HSE) is reminding construction companies of their duties to employees after a worker was paralysed in a fall.
Medtronic, Inc. (NYSE: MDT), announced that its Endeavor drug-eluting stent (DES) is the first and only coronary stent to have received CE (Conformité Européene) Mark approval for treating patients with acute coronary syndrome (ACS), which includes unstable angina and acute myocardial infarction (AMI), commonly known as heart attack.
New research from The Children"s Hospital of Philadelphia sheds light on the role of cell receptors in acting as gatekeepers for infectious viruses. By using mice genetically engineered to lack a particular receptor in heart and pancreas cells, the study team prevented infection by a common virus that causes potentially serious diseases in humans.
Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.
Your favourite painting could reveal a lot about your personality, this is a conclusion of a study published today, 23rd July 2009 in the British Journal of Psychology, which found that people"s preferences for painting genres is linked to key personality traits.
UK Advocates (UKA), a new charitable campaign group dedicated to helping the still suffering alcoholic achieve lasting sobriety, has welcomed the All Party Parliamentary Group (APPG) on Alcohol Misuse report published which calls for urgent action to address serious shortcomings in the treatment of alcohol dependents in England.
As the public face of health reform devolves into a partisan fight - with one GOP Senator [Jim DeMint, S.C.] saying the reform push is President Obama"s "Waterloo," and Democrats retorting that Republicans would derail the overhaul for political gain - a group of legislators in the Senate Finance Committee has continued to strive for a compromise behind closed doors, the Christian Science Monitor reports. "If a bipartisan compromise is to clear Congress this year, its main lines are likely to emerge here."
"Drug makers, advocacy groups, biotechnology firms and insurance companies have ratcheted up efforts to offer their two cents - and in most cases much, much more - in influencing the health care legislation now working its way through Congress," The New York Times reports. "Many familiar health groups in recent months have increased lobbying spending by more than $1 million, according to second-quarter lobbying records filed on Monday with the Senate Office of Public Records." Those groups include AARP and The Blue Cross and Blue Shield Association. Drug makers GlaxoSmithKline and Novartis, along with insurance company Allstate and biotechnology firm Amgen have also invested significantly more in lobbying activities."
"Nationally, about a quarter of all residency graduates began their medical training abroad. And in primary care - where there is a national shortage of physicians - more than half of all graduates are immigrants," The Concord Monitor reports. "New Hampshire"s primary care doctors are aging, and as they retire, recruiters said they will increasingly be replaced by physicians who began their training outside the country."
Fecal incontinence (FI) is a normal part of aging, or the perception that no treatment is available. Doctors may fail to comprehend patient hints about diarrhea and FI or may be reluctant to ask about fecal leakage, perhaps because of their own embarrassment or the perception that FI is a trivial concern.
Boston Scientific Corporation (NYSE: BSX) announced results from an analysis of economic and quality of life outcomes, based on one-year data from its landmark SYNTAX trial. The results found that percutaneous coronary intervention (PCI) using the TAXUS(R) Express2(R) Paclitaxel-Eluting Coronary Stent System was consistently associated with fewer patient hospital days during the first year after treatment compared to coronary artery bypass graft (CABG) surgery. Total medical costs at one year were also lower with PCI. Analysis of the data was presented by Ben van Hout, Ph.D., of the University of Utrecht, The Netherlands, at the annual EuroPCR Scientific Program in Barcelona.
Cancer stem-like cells have been implicated in the genesis of a variety of malignant cancers. Research scientists at Cedars-Sinai Medical Center"s Maxine Dunitz Neurosurgical Institute have isolated stem-like cells in benign (pituitary) tumors and used these "mother" cells to generate new tumors in laboratory mice. Targeting the cells of origin is seen as a possible strategy in the fight against malignant and benign tumors.
CareFusion Corporation, the company that will become publicly traded following the planned spinoff of the clinical and medical products businesses of Cardinal Health, announced it has expanded its Pyxis® perioperative offerings that integrate with leading operating room information systems (ORIS), incorporate radio-frequency identification (RFID) technology1 and include new services.
Funding from the American Recovery and Reinvestment Act will allow the National Institutes of Health to create jobs for early career scientists and increase the ranks of researchers and clinicians working in the global health field. With $3 million in funding over the next 18 months, the NIH"s Fogarty International Center will be able to support 23 additional participants in its Clinical Research Training Scholars and Fellows Program.
Feeling stressed? Then try savoring the scent of lemon, mango, lavender, or other fragrant plants. Scientists in Japan are reporting the first scientific evidence that inhaling certain fragrances alter gene activity and blood chemistry in ways that can reduce stress levels. Their study appears in ACS" Journal of Agricultural and Food Chemistry, a bi-weekly publication.
The American College for Advancement in Medicine (ACAM) has released its position regarding HB 3200, the health care reform bill proposed by the Obama administration. While ACAM believes healthcare reform is vital and necessary for America, it is our position that integrative medicine principles be included to yield the desired result of creating a more efficient, wellness-centered approach to healthcare.
Medicaid health plans are producing cost savings for states, increasing access to services for individuals covered by Medicaid, improving quality of care, and earning high satisfaction ratings from enrollees, according to a Lewin Group report released today by America"s Health Insurance Plans (AHIP). Twenty-four existing studies were analyzed by the Lewin Group to determine the savings achieved when states have implemented private Medicaid health plans.
The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer patients with underlying liver conditions.
Findings from the largest study to date comparing the efficacy of competing treatments for chronic hepatitis C infection (HCV) show that the regimens are similar when it comes to safety and their ability to provoke long-term viral eradication, according to researchers at Duke University Medical Center. Still, subgroup analysis reveals provocative data suggesting some approaches might be better than others for women and minorities.
When the Apollo 11 crew got back from the moon, 40 years ago this week, they showed no ill effects from seven days spent in weightlessness. But as American astronauts and Soviet cosmonauts began conducting longer-duration space flights, scientists noticed a disturbing trend: the longer humans stay in zero gravity, the more muscle they lose. Space travelers exposed to weightlessness for a year or more - such as those on a mission to Mars, for example - could wind up crippled on their return to Earth, unable to walk or even sit up.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, has announced that a study published online in the peer-reviewed journal Child and Adolescent Psychiatry and Mental Health found once-daily Vyvanse® (lisdexamfetamine dimesylate) CII significantly reduced the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 from the first time point measured (1.5 hours) up to the last time point assessed (13 hours) after administration. In this pediatric analog classroom study, treatment with Vyvanse was associated with significant improvement in behavior and attention in children at each time point measured, with improvement at 13 hours after administration.
A breakthrough technology adapted for breast cancer detection based in part on research originally sponsored by the Office of Naval Research (ONR) is set to air July 23 during a CNN International news segment on Vital Signs, a program hosted by Dr. Sanjay Gupta.
Ten years ago, the Institute of Medicine (IOM) sounded the alarm about the widespread toll of medical errors in a groundbreaking report call "To Err is Human." The report prompted a rush of congressional hearings and promises of reform. But in the decade since the report was published, little progress has been made implementing key reforms recommended by the IOM to improve patient safety, according to Consumers Union, the nonprofit publisher of Consumer Reports.
The UK will play a leading role in coordinated European action to tackle dementia from.
Injured heart tissue normally can"t regrow, but researchers at Children"s Hospital Boston have now laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects. In the July 24 issue of Cell, they show that a growth factor called neuregulin1 (NRG1), which is involved in the initial development of the heart and nervous system, can spur heart-muscle growth and recovery of cardiac function when injected systemically into animals after a heart attack.
The cost of insuring a family of four with an employer-sponsored health plan in the United States averaged $12,298 in 2008, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.
Ozone exposure, even at levels deemed safe by current clean air standards, can have a significant and negative effect on lung function, according to researchers at the University of California Davis.
The risk of developing deep vein thrombosis during a long flight is often overestimated. According to the German Institute for Quality and Efficiency in Health Care (IQWiG), this condition is very unlikely in healthy travellers. When people wear a cast or splint after a sports accident, on the other hand, many are not aware that they have an increased risk of deep vein thrombosis in their leg and pelvic area. This is emphasised in information published on IQWiG"s website Informed Health Online.
Sen. Lindsey Graham (R-S.C.) on Wednesday said he intends to vote for Supreme Court nominee Sonia Sotomayor, making him the fifth Republican senator to endorse the nominee, USA Today reports. Meanwhile, Senate Minority Whip Jon Kyl (R-Ariz.) became the 10th Republican to say that he will vote against her confirmation. During Sotomayor"s confirmation hearings last week, both Graham and Kyl "grilled her extensively," USA Today reports (Kiely/Brettschneider, USA Today, 7/23). According to Politico, Republicans privately estimate that Sotomayor could receive upward of 70 votes (Kady, Politico, 7/23). The Senate Judiciary Committee is scheduled to vote on the nomination Tuesday, followed by a full Senate vote late next week or the first week of August (Stanton, Roll Call, 7/22).According to CQ Today, Graham"s support could encourage other conservatives to back Sotomayor (Perine, CQ Today, 7/22). Graham said that Sotomayor "is definitely more liberal" than any Supreme Court nominee a Republican president would have chosen but that she also is "one of the most qualified" nominees in decades. He added, "I do believe that elections have consequences, and it"s not like we hid from the American people during the campaign that the Supreme Court nomination was at stake. The American people spoke" (USA Today, 7/23). Graham also said that he believes that Sotomayor "follows precedent" and "would not be an activist judge" (CQ Today, 7/22). He continued, "On balance, I do believe that the court will not dramatically change in terms of ideology with her selection," adding, "On some issues, quite frankly, (she) may be more balanced in her approach" (Hirschfeld Davis, AP/Boston Globe, 7/22).Kyl said, "Unfortunately, I have not been persuaded that Judge Sotomayor is absolutely committed to setting aside her biases and impartially deciding cases based upon the rule of law," adding, "And I cannot ignore her unwillingness to answer senators" questions straightforwardly" (Politico, 7/23).Broadcast Coverage NPR"s "All Things Considered" on Wednesday reported on Graham"s support of Sotomayor (Shapiro, "All Things Considered," NPR, 7/22).
The Australian Nursing Federation (ANF) welcomes the Federal Government"s announcement of funding to upgrade the skills of workers in aged care.
The routine call and review of Continuing Professional Development (CPD) records will begin
A shortage of doctors and nurses could damage health care reform. Analysis finds that more incentives are needed for primary care doctors and that most medical graduates choose better paid specialties. Meanwhile, a nurse temp agency forms in Texas to address the shortages there.
Police detectives searched the offices of one of Michael Jackson"s doctors for evidence of manslaughter on Wednesday, according to various US
The race to develop a H1N1 (swine flu) vaccine before the fall flu season ramped up Wednesday, after Australia launched the first human trials of the H1N1 vaccine and scientists from the U.S., China and Britain announced plans for human trials of an H1N1 vaccine in coming weeks, AFP/France24.com reports (7/23).
The Drugs Controller General of India (DCGI) asked state drug licensing authorities to avoid authorizing new licenses for single drug formulations of artemisinin and withdraw existing licences for these types of drugs by the end of this month, livemint.com reports. To prevent drug resistance, the WHO has advised against the use of drugs that only contain artemisinin to treat malaria and recommends using artemsinin in combination with other drugs. "India"s drug advisory body, the drug consultative committee, had in December approved the phasing out of the [artemisinin only] drug[s] from the market," livemint.com writes.
A San Mateo County, Calif., program that provides in-home case management services for people living with HIV/AIDS, as well as other programs that assist people living with the virus, could be eliminated, forcing patients to obtain more expensive outpatient care, if proposed state budget cuts are approved, the San Francisco Examiner reports. John Conley, director of public health programs for San Mateo County, said case management services are alternatives to hospitalization or nursing facility care, which are more expensive. "Additionally, the state"s AIDS office will not allow municipalities to make reductions to case management activities or other requirements such as client/staff ratios, according to county officials," the Examiner reports. Conley said, the state is paying half the costs of the program, but the program is "becoming very, very expensive to run" (Koskey, 7/23).
In a paper publishing online July 23 in Cell Stem Cell, a Cell Press journal, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China, report an important advance in the characterization of reprogrammed induced pluripotent stem cells, or iPSCs.
An event to mark the celebrate the 10th anniversary of the UQ Ipswich Campus and the launch of UQ"s teaching of Medicine at UQ Ipswich will be held today, Friday, July 24, 2009.
Need another reason to commit to a healthy diet and exercise? Think migraines are just headaches? Migraine and obesity sufferers feel more emotional pain than those dealing with life-threatening conditions like congestive heart failure, prostate cancer, osteoporosis and high blood pressure. In fact, they tend to feel more pessimistic than those diagnosed with depression.
Aradigm Corporation (OTCBB:ARDM) (the "Company") announced it received clearance from the U.S. Food and Drug Administration (FDA) for its inhaled liposomal ciprofloxacin Investigational New Drug (IND) application. The initial clinical protocol under this IND is an international, randomized, double-blind, placebo-controlled Phase IIb study designed to evaluate the Company"s inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis (BE). This orphan drug condition is a chronic severe respiratory disease and there is currently no drug specifically approved for its treatment in the U.S.
The Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMEA), has adopted a negative opinion for the use of Erbitux® (cetuximab) in combination with platinum-based chemotherapy for the treatment of patients with epidermal growth factor receptor (EGFR)-expressing, advanced or metastatic non-small cell lung cancer (NSCLC). Merck KGaA is evaluating potential appeal options requesting that the CHMP re-examine data demonstrating clinical relevant benefits to patients.
Appendicitis is a condition in which the appendix becomes swollen, inflamed, filled with pus. The appendix is a small pouch shaped like a small finger. It is on the right side of the abdomen, connected to the colon.
"House Democrats spent another day Thursday negotiating their health reform overhaul with few concrete signs of progress, heightening tensions and raising the possibility that leaders might bypass the House Energy and Commerce Committee and send the bill straight to the floor," CongressDailyAM reports. "The seven Blue Dog Coalition members on the panel emerged from a three-hour meeting with leaders and White House officials Thursday afternoon with little to say" (Hunt and House, 7/24).
Various news outlets examined the powerful roles members of the Obama administration are taking in the health care debate.
In an effort to trim medical costs, President Barack Obama is trying to strengthen the role of an independent commission to determine how much Medicare pays doctors and hospitals.
Asian Americans who have adopted more aspects of Western culture may be more likely to engage in behaviors that increase sun exposure, thereby endangering their skin health, according to a report in the May issue of Archives of Dermatology, one of the JAMA/Archives journals.
China"s $124 billion three-year "overhaul of its healthcare system needs to address the prescription of unnecessary drugs and treatments - a widespread practice relied upon to finance the medical sector, the World Bank said Thursday," China Daily/People"s Daily Online reports. The country"s "ambitious" reform efforts aim to "provide basic medical coverage and insurance to the country"s 1.3 billion people," according to the publication (7/24).
South African President Jacob Zuma and Virgin Group founder and chair Richard Branson "intend [on] establishing a disease control centre in South Africa as soon as next year," SAPA/The Times reports. "Branson said the initiative, expected to be launched by March, would be 50 percent private and 50 percent government funded," the news service writes (7/22).
Joel Weisman, "one of the first physicians to detect the AIDS epidemic and who became a national advocate for AIDS research, treatment and prevention," died on Saturday at his home in Westwood, Calif., the Los Angeles Times reports. Weisman was 66. Weisman was a general practitioner in southern California when in 1980 he first saw three ill gay men with a set of mysterious symptoms. He later contributed to the June 5, 1981 CDC Morbidity and Mortality Weekly Report, which "signaled the official start of the epidemic that the federal agency later named acquired immunodeficiency syndrome," according to the Times. Weisman was the founding chair of AIDS Project Los Angeles in 1983, helped organize the first dedicated hospital AIDS unit in Southern California and was an original board member of amfAR, the Foundation for AIDS Research (Woo, 7/23).
Merck Serono announced that it is seeking a European license for cladribine, its oral therapy that is in late-stage clinical trials for relapsing remitting MS.
Given Imaging LTD. (NASDAQ: GIVN) announced the launch of a simplified procedure for performing PillCam SB 2 capsule endoscopies for the detection of disease in the small intestine. Unveiled at the Society of Gastroenterology Nurses and Associates, Inc. (SGNA) 36th Annual Course, the new procedure utilizes two new products - SensorBelt and RecorderPouch - replacing the sensor array and the recorder belt used previously with the DataRecorder to record the wireless signals emitted by the capsule. Both products can be viewed at Given Imaging"s booth #623 at the SGNA meeting, taking place in St. Louis from May 15 to May 20.
Writers of a new report found "limited or suggestive evidence" that exposure to Agent Orange and other chemicals used in the Vietnam War is
In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery.
The Minister for Health and Children, Mary Harney TD, welcomed the publication of the report of the independent audit of retained organs in the State by Michaela Willis.
Roofing companies in Greater Manchester are being urged to make safety one of their top priorities after a man fell through the roof of a Swinton factory.
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that its lead drug candidate tamibarotene has received official notification from the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMEA) that a positive opinion was made regarding the application for orphan medicinal product for the treatment of acute promyelocytic leukemia (APL). The positive opinion of the COMP has now been forwarded to the EU commission for final approval and publication in the community register. This favorable opinion for tamibarotene in the European Union (EU) is in addition to the Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans retinoic acid (ATRA) and arsenic trioxide granted by the U.S. Food and Drug Administration (FDA) in October 2007.
Continuing efforts to help its members form lasting and profitable partnerships and pre-empt disputes in veterinary practice, the British Veterinary Association (BVA) has revised its "Guide to partnerships in veterinary practice". It will be of particular interest to vets buying into a partnership for the first time and will also be helpful to partners revising their existing agreement.
Medtronic, Inc. (NYSE: MDT) announced global resolution of all outstanding intellectual property litigation with Abbott Laboratories.
Crack open the latest medical textbook to the chapter on type 2, or adult-onset, diabetes, and you"ll be hard pressed to find the term "immunology" anywhere. This is because metabolic conditions and immunologic conditions are, with a few exceptions, distant cousins.
Striking differences in the risk factors for developing heart failure (HF) and patient prognosis exist between men and women. Men and women may also respond differently to treatment, raising concerns about whether current practices provide the best care and reinforcing the urgency for sex-specific clinical trials for HF, according to a review article published in the August 4, 2009, issue of the Journal of the American College of Cardiology.
Several newspapers recently published opinion pieces regarding President Obama"s commencement address at the University of Notre Dame. Summaries appear below.~ Cal Thomas, Washington Times: "Put aside the question of whether" Notre Dame should have invited President Obama to speak at its commencement ceremony on Sunday and "[f]ocus, instead, on [his] remarks and whether he is serious, or can be made so, about actually reducing the number of abortions in America," syndicated columnist Thomas writes in a Washington Times opinion piece. "Don"t put aside, however, the argument that there is only one reason to even want to reduce the number of abortions and that is that what is being killed, terminated, evacuated (choose your term) is, in fact, human life," Thomas adds. "In speaking of "original sin," the president hit upon why abortion has been so easily tolerated for so long," he writes, adding that Obama "spoke of "self-interest" and "crass materialism" but did so in the context of economics, not abortion." Thomas reports that Obama called for making adoption ""more available"" and providing ""care and support for women who do carry their children to term."" Thomas notes that Obama"s speech also included "an appeal for discussion and respect for people with different views," which was "a good beginning, but the ending is what counts, and the initial actions of this president when it comes to abortion and stem cell research have not been pro-life" (Thomas, Washington Times, 5/19).~ Tim Rutten, Los Angeles Times: After his commencement address at Notre Dame, "it"s now clear that the president is the rhetorical equivalent of a "money player,"" which is the "kind of competitor who steps up and delivers in the big games," Rutten writes in a Los Angeles Times opinion piece. Notre Dame"s invitation for Obama to speak at commencement and receive an honorary degree "bec[a]me an engine of controversy" because of protests from "reductionists," or conservative Catholics "who insist on bringing the broad sweep of Catholic social morality down to a single issue -- abortion," Rutten writes. However, Obama "negotiated the situation with remarkable ease," Rutten continues, adding that Obama was "speaking … to three audiences far from South Bend on Sunday." The first audience was the "crucial bloc of Catholic voters who seem to be looking for ways to remain in the Democratic Party," he writes. In addition, Obama was speaking to "those Catholic Democrats in public office ... who are under intense pressure from the reductionist bishops in their home dioceses" and to the U.S. Senate, which will likely ask Obama"s Supreme Court nominee about his or her views on abortion during confirmation hearings, Rutten continues. He concludes, "Even in Washington"s charged partisan atmosphere, it will be hard to ignore the president"s call for civility at Notre Dame" (Rutten, Los Angeles Times, 5/20).~ Clarence Page, Chicago Tribune: Obama "appropriately promoted" the "ability of adversaries to work together on mutual interests" in his commencement address, Page writes in a Tribune opinion piece. Page adds that the speech was "classic Obama the pragmatist: Look past ideology, try to ignore disagreements and work together on mutual interests." Obama said that "at some level, the views of the two camps are irreconcilable," Page writes, adding that it is "because Americans hold no values more dear than "life" and "choice."" Page adds that "[i]n the abortion debate, those values clash head-on." However, Obama"s "eloquent come-together oratory enabled him to leave the university like a hero, even though he glossed over the thorny specifics that drive wedges between people of goodwill when words are hammered into law," Page continues. "For now, by focusing on civility, the president apparently hopes to defuse the abortion powder keg long enough to address his higher priorities," Page writes, concluding, "The economy, national security and health care are going to be tough fight
Several news organizations have published lists to explain health care reform legislation.
The Society of Interventional Radiology hailed the extension of an
By proposing to reduce funding for abstinence-only sex education programs, "the Obama administration has reignited America"s sex education debate," Washington Times columnist Cheryl Wetzstein writes in an opinion piece. She says that the "usual answers" she receives from abstinence-only opponents when she asks about their criticism of the programs is that abstinence-only education "doesn"t work, it leaves kids ignorant about how to use birth control, it doesn"t serve gay kids, and (off the record) it"s just a return to the bad old days when unenlightened, sex-hating harpies ran sex education." According to Wetzstein, some proponents of abstinence-only programs believe that another factor -- which is "never mentioned" in the sex education debate -- "is how sexually active youth are part of the market for certain commercial sex- and disease-related products, and abstinent behavior reduces that market share."Wetzstein reports that she recently spoke with Pam Mullarkey, founder of Project SOS, who is "furious" that Presdient Obama"s budget proposal would reduce funding for abstinence-only programs and increase money for teen pregnancy prevention. Mullarkey claims that abstinence-only opponents "have spent so much money trying to destroy abstinence education" because "it directly costs them big bucks" if teens abstain. Wetzstein writes that she has "dim hopes for the survival of abstinence education as we"ve know it," concluding, "But should Congress decide to "follow the money," as Mrs. Mullarkey suggests, who knows what might turn up" (Wetzstein, Washington Times, 5/19).
"Premiums for small employers have been rising by double-digit increases for a few years, and they don"t have the negotiating power of larger employers," the Hartford (Conn.) Courant reports. This year"s increases are even higher than usual, on top of an economic recession. Connecticut businesses are resorting to drastic measures to preserve employee"s coverage, or are forced to drop it all together.
The WHO on Friday said the "H1N1 swine-flu virus could infect up to two billion people over the next two years - about one of every three people in the world," VOA News reports. According to the news service, "A separate WHO report Friday said the virus has spread to almost every country in the world, killing about 800 people since it emerged in April" (7/25).
The Oakland, Calif., chapter of the National Coalition of 100 Black Women on Saturday held a daylong conference, "Sistahs Getting Real About HIV/AIDS," that addressed HIV/AIDS among black women, the San Francisco Chronicle reports. The conference "focused on two issues that might seem contradictory: first, to convince women that they must take special precautions to protect themselves, and second, to let them know that an HIV diagnosis is not a death sentence," according to the Chronicle. Keynote speaker of the conference Tony Wafford, director of health and wellness for the National Action Network, said black women need to be more vocal with their partners about practicing safe sex and getting tested for HIV. Organizers noted that black women also "must address the stigma associated with HIV before they can talk openly about the risk of infection with their partners," the article states (Allday, 7/25).
A team of researchers from Case Western Reserve University School of Medicine have solved the mystery of why some children are more susceptible to malaria infection and anemia. These novel findings suggest that some children who are exposed to Plasmodium falciparum (P. falciparum) malaria before birth become tolerant to the malaria parasites, or their soluble products. This tolerance, which persists into childhood, reduces the ability of the immune system to attack and destroy parasites and increases the susceptibility of these children to develop a malaria infection. It also increases their risk for anemia. The study, published in this week"s issue of the open access journal, PLoS Medicine, is led by Indu Malhotra, Ph.D., and Christopher King, M.D., Ph.D., professor of international health, medicine, and pathology, with their colleagues at the Center for Global Health and Diseases at the Case Western Reserve University School of Medicine and their Kenyan colleagues at the Kenya Medical Research Institute and Division of Vector Borne Diseases.
The Rural Doctors Association of Australia (RDAA) will write to Prime Minister Kevin Rudd this week to invite him to participate in a national "fact finding" tour of rural hospitals, rural practices, health centres and Aboriginal Medical Services.
Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), July 28 - August 1, 2009, the foremost society for research into all aspects of eating and drinking behavior, finds that assisted reproductive techniques alter the expression of genes that are important for metabolism and the transport of nutrients in the placenta of mice. The results underscore the need for greater understanding of the long-term effects of new assisted reproductive techniques in humans.
Nearly all species have some ability to detect light. At least three types of cells in the retina allow us to see images or distinguish between night and day. Now, researchers at the Johns Hopkins School of Medicine have discovered in fish yet another type of cell that can sense light and contribute to vision.
Dr Gedis Grudzinskas the UK-based fertility expert issued the following statement in response to the statement by the Human Fertilisation and Embryology Authority:
An innovative nutritional supplement company, who are highly respected around the world for their ground-breaking and pioneering manufacturing technologies, will be showcasing their unique range of products at Hospitalar 2009; the largest healthcare technologies fair in Latin America.
Long-term survivors of cancer that developed in adulthood are at increased risk of experiencing serious psychological distress, according to a report in the July 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
In the race for faster, cheaper ways to read human genomes, Pacific Biosciences is hoping to set a new benchmark with technology that watches DNA being copied in real time. The device is being developed to sequence DNA at speeds 20,000 times faster than second-generation sequencers currently on the market and will ultimately have a price tag of $100 per genome.
Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.
Calypso Medical Technologies, Inc., announced the publication of data from a clinician sponsored investigational study conducted at the University of Pennsylvania, demonstrating the utility of the Calypso® System in tracking tumor movement in the pancreas. The data will be presented at the 51st Annual Meeting of the American Association of Physicists in Medicine (AAPM), July 26-30, at the Anaheim Convention Center. "In areas of the body, such as the pancreas, that are susceptible to respiratory motion it can prove difficult to handle the spectrum of motion that can arise," said James Metz, M.D., Clinical Director, Department of Radiation Oncology, The University of Pennsylvania Health System.
The University of Southern Nevada (USN) College of Nursing has been granted provisional approval by the Utah Board of Nursing to begin offering its 18-month Bachelor of Science in Nursing (BSN) program at the university"s campus located 10920 South River Front Parkway in South Jordan.
Evidence buried in the chromosomes of animals and plants strongly suggests only one group -- mammals -- have seen their genomes shrink after the dinosaurs" extinction. What"s more, that trend continues today, say Indiana University Bloomington scientists in the first issue of a new journal, Genome Biology and Evolution.
Health care experts at the University of California, San Francisco highlight in a new report the hidden risks and complexities that compromise patient safety for ambulatory patients with chronic disease.
A new proposal from the Centers for Medicare and Medicaid Services (CMS) to cut payments for radiation therapy treatments would cause many cancer centers to close, stop accepting Medicare patients, lay off support staff and reduce services to cancer patients, according to a survey conducted by ASTRO, the American Society for Radiation Oncology.
On Wednesday, July 29, U.S. Senate Special Committee on Aging Chairman Herb Kohl (D-WI) will hold a hearing on conflicts of interest in the fields of Continuing Medical Education (CME) and other medical research. As with many professions, physicians are required to participate in CME in order to maintain their license. In recent years, the pharmaceutical and medical device industries have increased their funding of CME, as well as other medical education programs, medical schools, and professional medical associations. The industries also pay physicians directly for their service as educational consultants. According to the Institute of Medicine, industry funding for accredited CME quadrupled from $302 million to $1.2 billion between 1998 and 2006.
÷£25 million announced to more than treble the number of NHS apprenticeships
Taro Pharmaceutical Industries Ltd. reported that it has received approval from the U.S. Food and Drug Administration ("FDA") for its Abbreviated New Drug Application ("ANDA") for cetirizine hydrochloride tablets (OTC), 5 mg and 10 mg ("Cetirizine Tablets"). The product will be marketed by Taro"s U.S. affiliate, Taro Pharmaceuticals U.S.A., Inc.
ARIAD Pharmaceuticals, Inc. (Nasdaq: ARIA) announced preliminary clinical data from an ongoing Phase 1 clinical trial of its investigational, multi-targeted kinase inhibitor, AP24534, in patients with advanced hematological cancers. The study results provide initial clinical evidence of hematologic, cytogenetic and molecular anti-cancer activity of AP24534 in heavily pretreated patients with resistant and refractory chronic myeloid leukemia (CML), including those with the T315I mutant variant of the target protein, Bcr-Abl. An abstract describing these data is being submitted for presentation at a major hematology meeting to be held later this year.
Cardium Therapeutics (NYSE Amex: CXM) and its subsidiary Tissue Repair Company (TRC) provided an update on the completion of their MATRIX Phase 2b clinical study and announced plans to provide detailed safety and efficacy data for their Excellarate(TM) product candidate around the end of September. The MATRIX trial, a prospective, randomized, double-blind, placebo-controlled study, has enrolled 124 diabetic patients with non-healing, lower extremity neuropathic ulcers.